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http://dspace-ipag.com.ua/jspui/handle/123456789/106
Полная запись метаданных
Поле DC | Значение | Язык |
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dc.contributor.author | Горбань, Н.Є. | - |
dc.contributor.author | Вовк, І.Б. | - |
dc.contributor.author | Нікитіна, І.М. | - |
dc.contributor.author | Кондратюк, В.К. | - |
dc.contributor.author | Ємець, Н.О. | - |
dc.date.accessioned | 2020-08-11T22:03:08Z | - |
dc.date.available | 2020-08-11T22:03:08Z | - |
dc.date.issued | 2020-08-12 | - |
dc.identifier.uri | http://dspace-ipag.com.ua/jspui/handle/123456789/106 | - |
dc.description.abstract | The aim of the study was to analyze the level of Ig M- and Ig G-antibody (Ab) for cytomegalovirus (CMV) and herpes simplex virus type 2 (HSV-2) in serum of women with non-atypical endometrial hyperproliferative pathology. Materials and methods: The analysis of immunoglobulin indices to CMV and HSV-2 in serum of women with non-atypical endometrial hyperproliferative pathology. In women with uterine body polyps the presence of CMV in the uterine cavity was found in 54.8% of cases, in women with non-atypical endometrial hyperplasia in 38.3% of cases. The levels of Ig G-Ab and Ig M-Ab to CMV in serum have a clear dependence on the degree of antigen expression in endometrial tissue. HSV-2 antigens were determined in 22.58 ± 5.31% of women with uterine body polyps and in 8.33 ± 3.57% of patients with non-atypical endometrial hyperplasia while increasing serum specific antibodies to HSV-2. Results: The results indicate that there is a clear link between viral infection of hyperproliferatively altered endometrium and the determination of positive immunoglobulin levels in peripheral blood, which may be a reliable marker of chronic persistent viral infection in a woman’s body. Conclusions: In women with uterine body polyps, the presence of CMV in the uterine cavity was found in 54.84 ± 6.32% of cases, in women with non-atypical endometrial hyperplasia in 38.33 ± 6.28% of cases. The levels of Ig G-Ab and and Ig M-Ab to CMV in serum have a clear dependence on the degree of antigen expression in endometrial tissue. HSV-2 antigens were determined in 22.58 ± 5.31% of women with uterine body polyps and in 8.33 ± 3.57% of patients with non-atypical endometrial hyperplasia while increasing serum specific antibodies to HSV-2. The results indicate that there is a clear link between viral infection of the target tissue (hyperproliferatively altered endometrium) and the determination of a positive level of peripheral blood immunoglobulin, which may be a reliable marker of chronic persistent viral infection in a woman. | uk_UA |
dc.language.iso | en | uk_UA |
dc.relation.ispartofseries | doi;10.36740/WLek202008102 | - |
dc.subject | Non-atypical endometrial hyperproliferative pathology, non-atypical endometrial hyperplasia, uterine body polyp, immunoglobulin to cytomegalovirus and genital herpes viruses | uk_UA |
dc.title | Immunoglobulin indicators to viruses cytomegal and genital herpes in the blood serum of women with non-atipical endometrial hyperprolifetative pathology | uk_UA |
dc.type | Other | uk_UA |
Располагается в коллекциях: | Відділення медичних та психосоціальних проблем здоров’я сім'і |
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Файл | Описание | Размер | Формат | |
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Immunoglobulin indicators to viruses cytomegal and genital herpes in the blood serum of women with non-atipical endometrial hyperprolifetative pathology.pdf | 365,28 kB | Adobe PDF | Просмотреть/Открыть |
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